Description

Methyl 2-Bromoquinoline-4-Carboxylate is a high-purity, versatile brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive bromine and ester functional groups, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for quinoline-based therapeutics targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Research: Used in developing novel pesticides, herbicides, and fungicides, leveraging the quinoline scaffold's bioactivity.
• Material Science Precursor: Employed in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its rigid, planar structure and functional handles.
• Chemical Synthesis: Serves as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions to introduce diverse substituents at the 2-position of the quinoline ring.
• Ligand and Catalyst Development: Utilized to synthesize novel nitrogen-containing ligands for coordination chemistry and catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	Methyl 2-Bromoquinoline-4-Carboxylate
CAS No.	103502-48-3
Molecular Formula	C11H8BrNO2
Molecular Weight	266.09 g/mol
Synonyms	2-Bromoquinoline-4-carboxylic acid methyl ester; Methyl 2-bromo-4-quinolinecarboxylate; 4-Quinolinecarboxylic acid, 2-bromo-, methyl ester; 2-Bromo-4-quinolinecarboxylic acid methyl ester; 2-Bromoquinoline-4-carboxylic acid methyl ester; Methyl 2-bromoquinoline-4-carboxylate; 103502-48-3
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromoquinoline-4-Carboxylate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.