Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound is a key synthetic precursor in the production of modern fluoroquinolone antibiotics, valued for its precise molecular structure that enables targeted therapeutic activity. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical synthesis facilities engaged in developing next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel fluoroquinolone antibiotic APIs.
• Antibacterial Drug Research: Used in R&D for developing new antibacterial compounds with improved efficacy and spectrum.
• Chemical Synthesis: Serves as a versatile intermediate for further functionalization and creation of derivative compounds.
• Process Development: Employed in scale-up and optimization studies for commercial API manufacturing routes.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Ethyl Ester
CAS No.	103460-87-3
Molecular Formula	C20H23F2N3O3
Molecular Weight	391.41 g/mol
Synonyms	Ethyl 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylate; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; Gatifloxacin Ethyl Ester; Gatifloxacin Intermediate; GTX Ethyl Ester; AM-1155 Ethyl Ester; BMS-206584-01
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6,8-Difluoro-1,4-Dihydro-7-(3-Methyl-1-Piperazinyl)-4-Oxo-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.