Description

(2S)-Pyrrolidinemethanamine Dihydrochloride is a high-purity chiral amine building block essential for the synthesis of complex pharmaceutical molecules. Its defined stereochemistry and dihydrochloride salt form provide critical advantages in drug development, offering enhanced stability and predictable reactivity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Agrochemical Research: Serves as a building block for novel chiral pesticides and herbicides, where specific stereochemistry can influence biological activity.
• Peptidomimetics: Incorporated into the design of peptide-like molecules to modulate their stability, bioavailability, and receptor binding properties.
• Chemical Biology Probes: Used in the synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: Potential precursor for chiral polymers or functionalized surfaces with specific recognition properties.

Basic Information

Product Name	(2S)-Pyrrolidinemethanamine Dihydrochloride
CAS No.	103382-84-9
Molecular Formula	C5H14Cl2N2
Molecular Weight	173.08 g/mol
Synonyms	(S)-(-)-2-(Aminomethyl)pyrrolidine Dihydrochloride; (S)-2-Pyrrolidinemethanamine Dihydrochloride; (S)-2-(Aminomethyl)pyrrolidine Hydrochloride; L-Prolinamine Dihydrochloride; (S)-Pyrrolidine-2-methanamine Dihydrochloride; (2S)-2-(Aminomethyl)pyrrolidine Dihydrochloride; (S)-2-Pyrrolidinylmethylamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our (2S)-Pyrrolidinemethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.