Description

n-(3-Oxobutyl) Norfloxacin is a key pharmaceutical intermediate in the synthesis of advanced fluoroquinolone antibiotics. This compound is critical for manufacturers requiring high-purity building blocks to ensure the efficacy and safety of the final active pharmaceutical ingredient (API). It is primarily utilized by pharmaceutical R&D laboratories and production facilities focused on developing and manufacturing antibacterial agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of Norfloxacin and its structural analogs.
• Antibacterial API Development: Used in research and development of new fluoroquinolone-based antibacterial agents.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for quinolone antibiotics.
• Reference Standard: Can be utilized as a standard in analytical methods for quality control of related pharmaceutical products.

Basic Information

Product Name	n-(3-Oxobutyl) Norfloxacin
CAS No.	103240-27-3
Molecular Formula	C19H21FN4O4
Molecular Weight	388.39 g/mol
Synonyms	1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid 3-Oxobutyl Ester; Norfloxacin 3-Oxobutyl Ester; 7-[4-(3-Oxobutyl)piperazin-1-yl]-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 1-Ethyl-6-fluoro-7-[4-(3-oxobutyl)piperazin-1-yl]-4-oxoquinoline-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our n-(3-Oxobutyl) Norfloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.