Description

(+)-Chloromethyl Menthyl Ether CAS NO 103128-76-3 is a chiral building block and reagent of significant value in asymmetric synthesis. Its primary importance lies in its ability to introduce a chiral menthyl auxiliary, enabling the stereoselective construction of complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity chiral intermediates.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to impart chirality in the synthesis of enantiomerically pure pharmaceuticals and bioactive compounds.
• Pharmaceutical Intermediate: Serves as a key precursor in the development of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Synthesis: Employed in the production of chiral pesticides and herbicides where biological activity is stereospecific.
• Fine Chemical Manufacturing: Utilized for the preparation of specialty chemicals, flavors, and fragrances that benefit from enantiomeric purity.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and catalysis research.
• Process Chemistry: Investigated for scalable, cost-effective routes to single-enantiomer products in pilot and commercial manufacturing.

Basic Information

Product Name	(+)-Chloromethyl Menthyl Ether
CAS No.	103128-76-3
Molecular Formula	C11H21ClO
Molecular Weight	204.74 g/mol
Synonyms	(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Chloromethyl Ether; (+)-Menthyl Chloromethyl Ether; (1R)-(-)-Menthyl Chloromethyl Ether; Chloromethyl (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ether; L-Menthyl Chloromethyl Ether; (-)-Menthyl Chloromethyl Ether (often refers to the same enantiomer); Chiral Menthyl Ether Derivative
EINECS	Contact for details

Quality Control

Our (+)-Chloromethyl Menthyl Ether is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by methods such as GC, HPLC, and NMR, to ensure it meets the exacting standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.