Description

6-Methoxy-Benzo[B]Thiophene-2-Carboxylic Acid is a high-purity, functionalized benzothiophene derivative that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its versatile molecular scaffold, which is essential for constructing complex heterocyclic compounds with targeted biological and material properties. This product is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, crop protection, and specialty polymer development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for enhanced biological activity and selectivity.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Chemical Synthesis Reagent: Employed in academic and industrial R&D for constructing complex benzothiophene-based libraries and exploring structure-activity relationships (SAR).
• Ligand and Catalyst Development: The carboxylic acid functionality allows for derivatization into chelating ligands used in catalytic systems and metal-organic chemistry.

Basic Information

Product Name	6-Methoxy-Benzo[B]Thiophene-2-Carboxylic Acid
CAS No.	102539-79-7
Molecular Formula	C10H8O3S
Molecular Weight	208.23 g/mol
Synonyms	6-Methoxybenzo[b]thiophene-2-carboxylic acid; 2-Carboxy-6-methoxybenzo[b]thiophene; 6-Methoxy-1-benzothiophene-2-carboxylic acid; 6-Methoxy-2-benzothiophenecarboxylic acid; 6-Methoxybenzo[b]thien-2-carboxylic acid; 102539-79-7; 6-Methoxybenzothiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Methoxy-Benzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and compliance with global regulatory expectations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.