Description

3'-Sialyl-n-Acetyllactosamine is a complex, biologically significant oligosaccharide derivative, widely recognized as a key intermediate in glycobiology research and synthesis. Its primary value lies in its role as a crucial building block for constructing sialylated glycoconjugates, which are essential for studying cell-cell recognition, immune response, and pathogen-host interactions. This high-purity compound is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly those developing glycan-based therapeutics, vaccines, and analytical standards.

Application

• Glycobiology Research: A fundamental substrate for enzymatic and chemical synthesis of complex sialylated oligosaccharides and glycans.
• Pharmaceutical Development: Serves as a critical intermediate in the production of sialyl Lewis X and other selectin ligand analogs for anti-inflammatory and anti-metastatic drug candidates.
• Diagnostic Reagent Synthesis: Used to prepare neoglycoconjugates and glycan arrays for studying protein-carbohydrate interactions and developing diagnostic assays.
• Enzymology Studies: Acts as a specific acceptor substrate for sialyltransferases to study enzyme kinetics, specificity, and for inhibitor screening.
• Bioconjugation: Employed in the chemoenzymatic synthesis of sialylated glycoproteins, glycolipids, and glycopolymers for therapeutic and material science applications.
• Standard Reference Material: Provides a high-purity standard for HPLC, MS, and NMR analysis in quality control and metabolic pathway studies.

Basic Information

Product Name	3'-Sialyl-n-Acetyllactosamine
CAS No.	102490-37-9
Molecular Formula	C31H52N2O23
Molecular Weight	844.75 g/mol
Synonyms	3'-Sialyllactosamine; Neu5Acα2-3Galβ1-4GlcNAc; 5-Acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosylonic acid-(2→3)-β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-D-glucopyranose; Sialyl Lewis X precursor; 3'-SLN; α-2,3-Sialyllactosamine; 3'-N-Acetylneuraminyllactosamine
EINECS	Contact for details

Quality Control

Our 3'-Sialyl-n-Acetyllactosamine is manufactured under stringent quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous analytical standards utilizing techniques such as HPLC, NMR, and MS for characterization, ensuring compliance with the exacting requirements of the life sciences industry.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details
Biological Activity	Suitable for enzymatic assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.