Description

5,5,8,8-Tetramethyl-2,3,5,6,7,8-Hexahydro-1H-Cyclopenta[B]Naphthalen-1-One is a high-purity, polycyclic ketone building block of significant interest in advanced organic synthesis. This compound matters for its rigid, fused-ring structure which serves as a versatile precursor for creating complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for applications such as ligand synthesis, fragrance development, and the creation of novel organic semiconductors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its stable polycyclic framework.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthetic musks and other complex aroma chemicals due to its tetramethyl-substituted, hydrogenated naphthalene core.
• Material Science Research: Investigated as a monomer or precursor for organic electronic materials, including semiconductors and light-emitting diodes (OLEDs).
• Catalyst & Ligand Development: The ketone functionality and sterically hindered structure make it a valuable starting point for designing novel chiral ligands and organocatalysts.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing and method development in quality control laboratories.

Basic Information

Product Name	5,5,8,8-Tetramethyl-2,3,5,6,7,8-Hexahydro-1H-Cyclopenta[B]Naphthalen-1-One
CAS No.	102296-82-2
Molecular Formula	C₁₇H₂₄O
Molecular Weight	244.37 g/mol
Synonyms	1H-Cyclopenta[b]naphthalen-1-one, 2,3,5,6,7,8-hexahydro-5,5,8,8-tetramethyl-; 5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-2H-cyclopenta[b]naphthalen-1-one; Tetramethyl hexahydro cyclopentanaphthalenone; Amberketone; Amber Ketone; Amberone; Musk ketone intermediate; Polycyclic ketone precursor.
EINECS	Contact for details

Quality Control

Our 5,5,8,8-Tetramethyl-2,3,5,6,7,8-Hexahydro-1H-Cyclopenta[B]Naphthalen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.