Description

(2S)-8-[(E)-3-Hydroxy-3-Methyl-1-Butenyl]-2α-Phenyl-7-Methoxychroman-4-One is a high-purity, synthetic chromanone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex organic structures for therapeutic applications.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct chromanone-based molecular frameworks.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Asymmetric Synthesis: Employed in reactions requiring high enantioselectivity due to its defined (2S) stereochemistry.
• Reference Standard: Used as an analytical standard in quality control and method development for related compounds.
• Biochemical Research: Investigated for its potential biological activity and interaction with specific enzymes or receptors.

Basic Information

Product Name	(2S)-8-[(E)-3-Hydroxy-3-Methyl-1-Butenyl]-2α-Phenyl-7-Methoxychroman-4-One
CAS No.	102275-31-0
Molecular Formula	C21H22O4
Molecular Weight	338.40 g/mol
Synonyms	(2S)-8-[(E)-3-Hydroxy-3-methylbut-1-en-1-yl]-2α-phenyl-7-methoxychroman-4-one; (S)-8-[(E)-3-Hydroxy-3-methyl-1-butenyl]-2α-phenyl-7-methoxychroman-4-one; 2α-Phenyl-7-methoxy-8-[(E)-3-hydroxy-3-methyl-1-butenyl]chroman-4-one, (2S)-; Chroman-4-one, 8-[(1E)-3-hydroxy-3-methyl-1-buten-1-yl]-2α-phenyl-7-methoxy-, (2S)-; (2S)-8-[(E)-3-Hydroxy-3-methylbut-1-enyl]-2α-phenyl-7-methoxychroman-4-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, enantiomeric excess, and impurity profiles. We adhere to a cGMP-compliant quality management system to ensure traceability and batch-to-batch consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.