Description

Adenosine 5'-Diphosphomannose, Disodium Salt is a high-purity biochemical reagent, a nucleotide sugar derivative essential for glycosylation reactions in biological systems. This compound serves as a critical mannose donor in the enzymatic synthesis of glycoproteins, glycolipids, and oligosaccharides. It is primarily utilized by researchers and manufacturers in the fields of glycobiology research, enzymatic synthesis, and pharmaceutical development for studying and producing complex carbohydrate structures.

Application

• Glycobiology Research: As a key substrate for studying glycosyltransferase enzymes and metabolic pathways involving mannose incorporation.
• Enzymatic Synthesis: Used as a mannosyl donor in the in vitro enzymatic synthesis of defined oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Development: Employed in the research and production of glycosylated biopharmaceuticals, including monoclonal antibodies and therapeutic proteins.
• Biochemical Assays: Serves as a standard or reagent in assays designed to measure glycosyltransferase activity or screen for enzyme inhibitors.
• Metabolic Studies: Used to investigate disorders of glycosylation (CDG) and other metabolic diseases related to nucleotide sugar metabolism.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of diagnostic kits for enzymatic activity measurements.

Basic Information

Product Name	Adenosine 5'-Diphosphomannose, Disodium Salt
CAS No.	102208-02-6
Molecular Formula	C16H23N5Na2O16P2
Molecular Weight	673.29 g/mol
Synonyms	ADP-Mannose, Disodium Salt; Adenosine 5'-(trihydrogen diphosphate) P'→5'-ester with D-mannose, disodium salt; GDP-Mannose Analog; ADP-D-Mannose; Adenosine diphosphate mannose; 5'-ADP-Mannose; Mannose-ADP
EINECS	Contact for details

Quality Control

Our Adenosine 5'-Diphosphomannose, Disodium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and potency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the product to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
pH (1% Solution)	6.0 - 8.0
Endotoxin	< 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.