Description

Boc-Phe(4-No2)-Oh Dcha CAS NO 102185-42-2 is a protected amino acid derivative, specifically N-Boc-4-nitro-L-phenylalanine dicyclohexylamine salt, widely used as a key chiral building block in organic synthesis. This compound is essential for the controlled introduction of the 4-nitrophenylalanine moiety into peptide chains and other complex molecules, offering a balance of reactivity and stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A crucial intermediate in solid-phase and solution-phase peptide synthesis (SPPS) for incorporating modified phenylalanine residues.
• Pharmaceutical Research: Serves as a building block in the research and development of new therapeutic agents, including enzyme inhibitors and receptor ligands.
• Chemical Biology: Used in the synthesis of labeled peptides and probes for studying protein-protein interactions and cellular processes.
• Process Chemistry: Employed in the scalable synthesis of complex organic molecules and APIs requiring protected amino acid precursors.
• Academic Research: A valuable reagent for university and institutional labs focused on synthetic organic chemistry and medicinal chemistry projects.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	Boc-Phe(4-No2)-Oh Dcha
CAS No.	102185-42-2
Molecular Formula	C26H41N3O6
Molecular Weight	491.62 g/mol
Synonyms	N-Boc-4-nitro-L-phenylalanine dicyclohexylamine salt; (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-nitrophenyl)propanoic acid dicyclohexylamine salt; Boc-4-NO2-Phe-OH·DCHA; Boc-L-4-nitrophenylalanine DCHA salt; tert-Butyloxycarbonyl-4-nitro-L-phenylalanine dicyclohexylammonium salt; N-(tert-Butoxycarbonyl)-4-nitro-L-phenylalanine dicyclohexylamine salt; BOC-PHE(4-NO2)-OH DCHA SALT
EINECS	Contact for details

Quality Control

Our Boc-Phe(4-No2)-Oh Dcha is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.