Description

Hex-5-Yn-1-Amine Hydrochloride is a versatile alkyne-functionalized amine salt, a key building block in advanced organic synthesis and pharmaceutical research. Its reactive terminal alkyne and primary amine groups make it a crucial intermediate for constructing complex molecular architectures via click chemistry and amide coupling reactions. This high-purity compound is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science, where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring alkyne handles for bioconjugation or further functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate amine and alkyne functionalities.
• Click Chemistry Reagent: An ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, enabling the rapid and modular assembly of complex molecules for drug discovery and material science.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating functional polymers, dendrimers, and smart materials with tailored properties.
• Bioconjugation & Probe Development: Utilized for labeling biomolecules (proteins, peptides, nucleic acids) with fluorescent dyes, affinity tags, or other reporter groups.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Hex-5-Yn-1-Amine Hydrochloride
CAS No.	102169-54-0
Molecular Formula	C6H12ClN
Molecular Weight	133.62 g/mol
Synonyms	5-Hexyn-1-amine hydrochloride; 6-Amino-1-hexyne hydrochloride; 1-Amino-5-hexyne hydrochloride; Pent-4-yn-1-ylmethylamine hydrochloride; 5-Hexynylamine hydrochloride; 5-Hexyne-1-amine HCl; 1-Hexyne-6-amine hydrochloride
EINECS	Contact for details

Quality Control

Our Hex-5-Yn-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.