Description

2-Iodo-3-Nitronaphthalene is a halogenated nitronaphthalene derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique structure, combining an iodine substituent with a nitro group on the naphthalene ring system, makes it a critical building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of functional dyes or liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly useful in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and pesticides, where the naphthalene core provides a stable scaffold for bioactive molecules.
• Organic Electronic Materials: Used in the research and development of organic semiconductors, charge-transport materials, and non-linear optical (NLO) materials due to its electron-accepting nitro group and potential for further functionalization.
• Dye and Pigment Synthesis: Acts as an intermediate for creating specialized azo dyes, pigments, and fluorescent markers, where the iodine atom allows for further structural elaboration.
• Ligand and Catalyst Development: Utilized in academic and industrial research to synthesize novel ligands for metal catalysis or as a model substrate in methodological studies.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying biological processes, leveraging the reactivity of the iodine for bioconjugation strategies.

Basic Information

Product Name	2-Iodo-3-Nitronaphthalene
CAS No.	102153-71-9
Molecular Formula	C₁₀H₆INO₂
Molecular Weight	299.07 g/mol
Synonyms	3-Nitro-2-iodonaphthalene; 2-Iodo-3-nitro-naphthalene; Naphthalene, 2-iodo-3-nitro-; 2-Iodonaphthalene, 3-nitro-; 102153-71-9; 3-Nitro-2-iodonaphthalene; 2-Iodo-3-nitro naphthalene
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Nitronaphthalene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles. We are committed to meeting the stringent requirements of our global customer base in fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents (e.g., DMF, DMSO, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.