Description

(1S)-7-Isopropylidene-1,2,3,5,6,7,8,8Aβ-Octahydro-1β-Hydroxy-1,4-Dimethylazulen-6-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex azulene-derived structure. This compound is critical for enabling precise stereochemistry and functional group transformations in sophisticated synthetic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers for the development and production of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, particularly in oncology and anti-inflammatory research.
• Organic Synthesis Research: Used in academic and industrial R&D for exploring new reactions and methodologies involving fused ring systems.
• Fine Chemical Production: Serves as a precursor for the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Material Science: Investigated as a monomer or precursor for creating novel organic electronic materials and polymers with unique optical properties.

Basic Information

Product Name	(1S)-7-Isopropylidene-1,2,3,5,6,7,8,8Aβ-Octahydro-1β-Hydroxy-1,4-Dimethylazulen-6-One
CAS No.	102130-91-6
Molecular Formula	C₁₅H₂₂O₂
Molecular Weight	234.33 g/mol
Synonyms	(1S,4S,8aS)-7-Isopropylidene-1,2,3,5,6,7,8,8a-Octahydro-1-hydroxy-1,4-dimethylazulen-6-one; 1β-Hydroxy-1,4-dimethyl-7-isopropylideneoctahydroazulen-6-one; (-)-7-Isopropylideneoctahydro-1β-hydroxy-1,4-dimethylazulen-6-one; Azulen-6-one derivative; Guaiene derivative. Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of (1S)-7-Isopropylidene-1,2,3,5,6,7,8,8Aβ-Octahydro-1β-Hydroxy-1,4-Dimethylazulen-6-One adheres to stringent quality management systems. The product undergoes rigorous analytical testing, including chiral HPLC, NMR, and GC-MS, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.