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n-Acetyl-α-D-Galactosamine 1-Phosphate, Sodium Salt CAS NO 102029-78-7


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CAS No.:102029-78-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Acetyl-α-D-Galactosamine 1-Phosphate, Sodium Salt is a crucial biochemical intermediate and activated sugar nucleotide precursor. This compound matters for its role in the biosynthesis of glycoproteins and glycolipids, serving as a key substrate for glycosyltransferases. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for enzyme studies, oligosaccharide synthesis, and the development of therapeutic agents.

Application

  • Biochemical Research: Used as a high-purity substrate for studying the kinetics and mechanisms of specific glycosyltransferases, particularly those involved in O-glycosylation pathways.
  • Enzymatic Synthesis: Serves as a donor molecule in the in vitro enzymatic synthesis of complex oligosaccharides, glycopeptides, and glycolipids for structural and functional studies.
  • Pharmaceutical Development: Employed in the research and development of novel therapeutics targeting glycosylation-related diseases, including certain cancers and congenital disorders of glycosylation (CDGs).
  • Diagnostic Reagent Production: Acts as a key component in formulating enzyme-coupled assays and diagnostic kits for measuring glycosyltransferase activity in clinical samples.
  • Glycoengineering: Utilized in cell-free systems and metabolic engineering approaches to produce tailored glycoconjugates with desired biological properties.

Basic Information

Product Name n-Acetyl-α-D-Galactosamine 1-Phosphate, Sodium Salt
CAS No. 102029-78-7
Molecular Formula C8H14NNaO10P
Molecular Weight 338.16 g/mol
Synonyms α-D-GalNAc-1-phosphate sodium salt; UDP-GalNAc precursor; N-Acetyl-α-D-galactosamine 1-phosphate sodium salt; 2-Acetamido-2-deoxy-α-D-galactopyranose 1-phosphate sodium salt; GalNAc-α-1-P sodium salt; Acetylgalactosamine phosphate sodium salt; Sodium (2-acetamido-2-deoxy-α-D-galactopyranosyl) phosphate
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Quality Control

Our n-Acetyl-α-D-Galactosamine 1-Phosphate, Sodium Salt is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for biochemical and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95%
Assay ≥ 90% (anhydrous basis)
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Bacterial Endotoxins < 10 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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