Description

6-Chloro-3-Nitroquinolin-4-Ol is a versatile and high-purity quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and nitrated structure makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and pesticides, leveraging its bioactive quinoline core.
• Material Science: Serves as a building block for creating organic ligands, dyes, and photoactive compounds used in electronic materials and sensors.
• Chemical Synthesis: An important reagent for introducing the chloro-nitroquinolinol moiety into more complex molecular architectures in academic and industrial R&D.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme interactions and biological pathways.

Basic Information

Product Name	6-Chloro-3-Nitroquinolin-4-Ol
CAS No.	101861-61-4
Molecular Formula	C9H5ClN2O3
Molecular Weight	224.60 g/mol
Synonyms	4-Hydroxy-6-chloro-3-nitroquinoline; 6-Chloro-3-nitro-4-quinolinol; 6-Chloro-4-hydroxy-3-nitroquinoline; 3-Nitro-6-chloroquinolin-4-ol; Quinolin-4-ol, 6-chloro-3-nitro-; 6-Chloro-3-nitroquinoline-4-ol
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Nitroquinolin-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flames. For long-term storage, consider maintaining the material under an inert atmosphere such as nitrogen or argon to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.