Description

Boc-D-Dab(Z)-Oh Dcha is a protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity, stereochemically defined intermediates for complex molecule construction. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of the diaminobutyric acid (Dab) residue with orthogonal protecting groups.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptide sequences and cyclic peptides in solution.
• Pharmaceutical Research: Serves as a crucial precursor in the research and development of new peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Employed in the creation of peptide-protein or peptide-small molecule conjugates for targeted drug delivery systems.
• Chemical Biology Probes: Used to synthesize labeled or modified peptides for studying biological processes and protein interactions.
• Antibiotic & Antimicrobial Peptide Development: A building block for creating novel antimicrobial peptides where diaminobutyric acid residues are often significant.

Basic Information

Product Name	Boc-D-Dab(Z)-Oh Dcha
CAS No.	101854-42-6
Molecular Formula	C26H41N3O6
Molecular Weight	491.63 g/mol
Synonyms	Nα-Boc-Nγ-Z-D-diaminobutyric acid dicyclohexylamine salt; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-((tert-butoxycarbonyl)amino)butanoic acid; Boc-D-Dab(Z)-OH·DCHA; Boc-D-Dab(Z)-O-DCHA; Fmoc-D-Dab(Boc)-OH (Note: This is a related Fmoc-protected variant); D-Diaminobutyric acid derivative; D-Dab(Boc,Z)-OH DCHA salt
EINECS	Contact for details

Quality Control

Our Boc-D-Dab(Z)-Oh Dcha is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards for fine chemical and pharmaceutical intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.