Description

2-Norbornanecarboxylic Acid, 2-Chloro- is a specialized bicyclic organic compound featuring a carboxylic acid group and a chlorine substituent on the norbornane skeleton. This unique structure makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for creating complex molecules with specific stereochemistry. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those requiring rigid, bicyclic frameworks.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the norbornane structure can contribute to biological activity and environmental stability.
• Advanced Material Research: Serves as a monomer or precursor for developing specialty polymers, resins, and liquid crystals with unique thermal and mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex fragrances, flavors, and other high-value specialty chemicals.
• Academic & Industrial R&D: Utilized in methodological studies and process chemistry development for constructing stereochemically defined carbon skeletons.

Basic Information

Product Name	2-Norbornanecarboxylic Acid, 2-Chloro-
CAS No.	101774-57-6
Molecular Formula	C8H11ClO2
Molecular Weight	174.62 g/mol
Synonyms	2-Chloronorbornane-2-carboxylic Acid; 2-Chlorobicyclo[2.2.1]heptane-2-carboxylic Acid; 2-Chloro-2-norbornanecarboxylic Acid; 2-Chloro-2-carboxybicyclo[2.2.1]heptane; endo/exo-2-Chloronorbornane-2-carboxylic Acid (mixture); Bicyclo[2.2.1]heptane-2-carboxylic acid, 2-chloro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-2-norbornanecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, chiral purity (enantiomeric excess), and impurity profiles. Our quality systems support development and cGMP manufacturing requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.