Description

Heptosyl-2-Keto-3-Deoxyoctonate is a key intermediate in the biosynthesis of lipopolysaccharides (LPS), specifically within the inner core region of Gram-negative bacterial cell walls. Its precise structure makes it an essential building block for research into bacterial pathogenesis and the development of novel therapeutics and diagnostics. This compound is primarily utilized by researchers and manufacturers in the fields of glycobiology, vaccine development, and synthetic chemistry.

Application

• Glycobiology Research: As a critical precursor for studying the assembly and function of lipopolysaccharide (LPS) structures.
• Vaccine & Therapeutic Development: Used in the synthesis of carbohydrate-based antigens for conjugate vaccines targeting Gram-negative bacteria.
• Enzyme Substrate & Inhibitor Studies: Serves as a substrate for enzymes involved in LPS biosynthesis, such as glycosyltransferases.
• Synthetic Chemistry Intermediate: A valuable chiral starting material for the total synthesis of complex bacterial oligosaccharides.
• Diagnostic Reagent Production: Employed in the development of immunoassays and detection kits for bacterial endotoxins.
• Microbiology & Pathogenesis Research: Essential for investigating bacterial cell wall integrity, host-pathogen interactions, and antibiotic resistance mechanisms.

Basic Information

Product Name	Heptosyl-2-Keto-3-Deoxyoctonate
CAS No.	101769-91-9
Molecular Formula	C15H24O11
Molecular Weight	380.35 g/mol
Synonyms	KDO-Heptose; 3-Deoxy-D-manno-oct-2-ulosonic acid-(2→4)-L-glycero-D-manno-heptose; Heptosyl-KDO; LPS Core Intermediate; ADP-L-glycero-D-manno-heptose:3-deoxy-D-manno-oct-2-ulosonate 4-heptosyltransferase substrate; 4-O-[(3-Deoxy-α-D-manno-oct-2-ulopyranosyl)onic acid]-L-glycero-D-manno-heptose
EINECS	Contact for details

Quality Control

Our Heptosyl-2-Keto-3-Deoxyoctonate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.