Description

(R)-(-)-1,1'-Bi(2-Naphthyl Diacetate) is a high-purity chiral intermediate of significant importance in asymmetric synthesis. Its primary value lies in its role as a precursor for the synthesis of enantiomerically pure BINOL derivatives, which are crucial ligands and catalysts in organic chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high optical purity for developing novel active ingredients and functional molecules.

Application

• Asymmetric Catalysis: Key precursor for synthesizing chiral (R)-BINOL and its derivatives, which serve as privileged ligands in metal-catalyzed asymmetric reactions.
• Pharmaceutical Intermediates: Used in the research and production of enantiomerically pure active pharmaceutical ingredients (APIs) where stereochemistry is critical for efficacy.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides to enhance selectivity and reduce environmental impact.
• Material Science: Building block for creating chiral polymers, liquid crystals, and other functional materials with specific optical properties.
• Academic & Industrial Research: A valuable tool for chemists exploring new methodologies in stereoselective synthesis and catalysis.

Basic Information

Product Name	(R)-(-)-1,1'-Bi(2-Naphthyl Diacetate)
CAS No.	101758-48-9
Molecular Formula	C24H18O4
Molecular Weight	370.40 g/mol
Synonyms	(R)-(-)-1,1'-Bi-2-naphthyl Diacetate; (R)-BINOL Diacetate; (R)-1,1'-Binaphthalene-2,2'-diyl Diacetate; (R)-2,2'-Diacetoxy-1,1'-binaphthyl; (R)-(-)-2,2'-Bis(acetoxy)-1,1'-binaphthyl; (R)-BINOL Di-O-acetate; (R)-1,1'-Binaphthyl-2,2'-diyl Diacetate
EINECS	Contact for details

Quality Control

Our (R)-(-)-1,1'-Bi(2-Naphthyl Diacetate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.