Description

4(1H)-Pteridinone,5,6,7,8-Tetrahydro-6,7-Dimethyl-,(6R-Cis)-(9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique cis-dimethylated tetrahydroperidinone structure makes it a valuable chiral building block and a key intermediate for developing novel active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of complex drug candidates, particularly those targeting enzymatic pathways.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Research: Potential application as an analog or inhibitor in studies related to folate metabolism and other pteridine-dependent biological processes.
• Fine Chemical Synthesis: Employed as a specialized building block for constructing complex, polycyclic molecular architectures in custom synthesis projects.
• Agrochemical Development: Investigated as an intermediate for novel crop protection agents due to its heterocyclic core.
• Academic Research: Utilized in universities and research institutes for methodological studies in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	4(1H)-Pteridinone,5,6,7,8-Tetrahydro-6,7-Dimethyl-,(6R-Cis)-(9Ci)
CAS No.	101629-11-2
Molecular Formula	C8H12N4O
Molecular Weight	180.21 g/mol
Synonyms	(6R-cis)-5,6,7,8-Tetrahydro-6,7-dimethyl-4(1H)-pteridinone; (6R,7S)-5,6,7,8-Tetrahydro-6,7-dimethyl-1H-pteridin-4-one; Tetrahydro-6,7-dimethyl-4(1H)-pteridinone (cis-6R); L-Biopterin analog intermediate; 6,7-cis-Dimethyl-5,6,7,8-tetrahydropterin-4-one
EINECS	Contact for details

Quality Control

Our production of 4(1H)-Pteridinone,5,6,7,8-Tetrahydro-6,7-Dimethyl-,(6R-Cis)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We employ advanced analytical techniques including HPLC, chiral HPLC, NMR, and MS to verify identity and quality, meeting the exacting standards required for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.