Description

Naphthalene, 1,2,3,4,4A,5,6,7-Octahydro-8-Methoxy- CAS NO 101555-42-4 is a methoxy-substituted, partially hydrogenated naphthalene derivative, serving as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique fused-ring structure with a methoxy functional group makes it a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those with polycyclic frameworks, such as certain classes of antivirals, CNS-active agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides where the hydrogenated naphthalene core provides specific biological activity and stability.
• Material Science Research: Acts as a monomer or a functional unit in the development of advanced polymers, liquid crystals, and organic semiconductors due to its rigid, planar structure.
• Fragrance and Flavor Chemistry: Serves as a starting material for synthesizing specific musk-like or woody aroma chemicals after further chemical modification.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for Diels-Alder reactions, catalytic hydrogenation studies, and as a scaffold for library synthesis in medicinal chemistry.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the methoxy-substituted tetralin structure influences color and lightfastness properties.

Basic Information

Product Name	Naphthalene, 1,2,3,4,4A,5,6,7-Octahydro-8-Methoxy-
CAS No.	101555-42-4
Molecular Formula	C₁₁H₁₆O
Molecular Weight	164.24 g/mol
Synonyms	8-Methoxy-1,2,3,4,4a,5,6,7-octahydronaphthalene; 8-Methoxytetralin; 1,2,3,4-Tetrahydro-8-methoxynaphthalene; 5-Methoxy-1,2,3,4-tetrahydronaphthalene (isomer); Octahydro-8-methoxynaphthalene; 8-Methoxy-1,2,3,4-tetrahydronaphthalene; Methoxytetralin; 8-Methoxy-1,2,3,4-tetrahydronaphthalene (common name)
EINECS	Contact for details

Quality Control

Our Naphthalene, 1,2,3,4,4A,5,6,7-Octahydro-8-Methoxy- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure consistent quality and batch-to-batch reproducibility. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.