Description

Technetium Medronate is a radiopharmaceutical complex used as a diagnostic imaging agent. This compound is critical for nuclear medicine procedures, enabling the visualization of bone metabolism and pathology. It is primarily utilized by radiopharmacies, hospitals, and diagnostic imaging centers for skeletal scintigraphy to detect abnormalities such as metastases, infections, and fractures.

Application

• Skeletal Scintigraphy (Bone Scan): Primary diagnostic tool for imaging the skeleton to detect bone metastases, osteomyelitis, and fractures.
• Oncology Imaging: Used to stage and monitor the progression of cancers known to metastasize to bone, such as breast and prostate cancer.
• Orthopedic Evaluation: Assesses prosthetic joint complications, sports injuries, and unexplained bone pain.
• Metabolic Bone Disease Assessment: Aids in the evaluation of conditions like Paget's disease of bone.
• Radiopharmaceutical Kit Formulation: Serves as the active pharmaceutical ingredient (API) in cold kits for the on-site preparation of Tc-99m Medronate.
• Research & Development: Used in preclinical and clinical research for developing new diagnostic protocols and studying bone physiology.

Basic Information

Product Name	Technetium Medronate
CAS No.	101488-09-9
Molecular Formula	C4H6O8P2Tc
Molecular Weight	388.96 g/mol (for Tc-99 isotope)
Synonyms	Technetium Tc 99m Medronate; Tc-99m MDP; Methylene Diphosphonate, Technetium Complex; Technetium-99m Medronate; Medronate Technetium (99mTc); (99mTc)Medronate; Technetium (99mTc) Methylenediphosphonate; MDP Kit (Tc-99m)
EINECS	Contact for details

Quality Control

Our Technetium Medronate is manufactured under strict quality systems suitable for radiopharmaceutical applications. Each batch is tested to ensure compliance with relevant pharmacopoeial standards (e.g., USP monographs for radiopharmaceuticals) for critical parameters including radiochemical purity, radionuclidic purity, and sterility. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is strictly light-sensitive and must be protected from all light exposure during storage and handling to maintain stability.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC/Radio-TLC)	Conforms to standard
Radiochemical Purity (RCP)	≥ 95.0%
Radionuclidic Purity	≥ 99.9% (Tc-99m)
pH	5.0 - 7.0
Sterility	Sterile
Bacterial Endotoxins	< 175 EU/Vial
Assay (Radioactivity)	90.0 - 110.0% of declared value at reference time

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.