Description

4-Nitrophenyl-α-Mannopyranoside 6-(α-Galactopyranosyl Phosphate) is a specialized synthetic glycoside derivative designed for advanced biochemical research and diagnostic applications. This compound serves as a critical chromogenic substrate for the detection and kinetic study of specific glycosidase and phosphatase enzymes. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in enzymology, carbohydrate chemistry, and the development of novel therapeutic targets.

Application

• Enzyme Substrate for Research: Acts as a chromogenic substrate for studying the activity and inhibition of α-mannosidases, α-galactosidases, and related phosphorylases in vitro.
• Diagnostic Assay Development: Used in the formulation of diagnostic kits for detecting enzyme deficiencies or abnormalities, such as those related to lysosomal storage disorders.
• Biochemical Pathway Analysis: Employed in research to elucidate specific carbohydrate metabolic pathways and glycosylation processes.
• High-Throughput Screening (HTS): Suitable for use in HTS platforms to identify potential drug candidates that modulate glycosidase enzyme activity.
• Quality Control in Biologics: Can be used to monitor enzyme activity during the production and purification of therapeutic proteins.
• Academic & Industrial Research: A key reagent for universities and R&D departments focusing on glycobiology, enzymology, and chemical biology.

Basic Information

Product Name	4-Nitrophenyl-α-Mannopyranoside 6-(α-Galactopyranosyl Phosphate)
CAS No.	101455-35-0
Molecular Formula	C18H26NO16P
Molecular Weight	519.37 g/mol
Synonyms	p-Nitrophenyl α-D-mannopyranoside 6-(α-D-galactopyranosyl phosphate); 4-Nitrophenyl α-D-mannopyranoside 6-(α-D-galactopyranosyl phosphate); α-D-Galp-(1→6)-α-D-Manp-OC6H4-p-NO2 phosphate; PNPM 6-(α-Gal phosphate); 4-Nitrophenyl α-mannoside 6-α-galactosyl phosphate; Chromogenic glycoside-phosphate conjugate
EINECS	Contact for details

Quality Control

Every batch of 4-Nitrophenyl-α-Mannopyranoside 6-(α-Galactopyranosyl Phosphate) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.