Description

3-Carboxy-5-Nitrophenylboronic Acid is a multifunctional boronic acid derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a carboxylic acid and a nitro group ortho to the boronic acid moiety, makes it a valuable building block for constructing complex molecules and functional materials. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications such as Suzuki-Miyaura cross-coupling reactions and sensor development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring boronic acid functionality for coupling or as a pharmacophore.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactivity in cross-coupling reactions to create diverse chemical scaffolds.
• Material Science & Polymer Chemistry: Employed in the creation of advanced polymers, covalent organic frameworks (COFs), and other functional materials where its bifunctional groups allow for precise structural control.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential in medicinal chemistry and material synthesis.
• Chemical Sensor Development: Utilized in the design and fabrication of boronic acid-based sensors for the detection of sugars, anions, and other analytes due to its specific binding properties.
• Research & Development (R&D): Serves as a valuable reagent in academic and industrial R&D laboratories for exploring new synthetic methodologies and chemical biology tools.

Basic Information

Product Name	3-Carboxy-5-Nitrophenylboronic Acid
CAS No.	101084-81-5
Molecular Formula	C7H6BNO6
Molecular Weight	210.94 g/mol
Synonyms	(3-Carboxy-5-nitrophenyl)boronic acid; 5-Nitro-3-carboxyphenylboronic acid; 3-Borono-5-nitrobenzoic acid; Boronic acid, B-(3-carboxy-5-nitrophenyl)-; 3-Carboxy-5-nitrobenzeneboronic acid; 101084-81-5; 3-Carboxy-5-nitrophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Carboxy-5-Nitrophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment, NMR for structural confirmation, and titration for assay determination, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent decomposition. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	95.0% - 105.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.