Description

2-Hydroxy-1-Methylthioindane is a specialized sulfur-containing indane derivative with significant utility in advanced organic synthesis. This compound serves as a versatile chiral building block and intermediate for the development of pharmaceuticals, agrochemicals, and functional materials. Key industries that require this high-purity intermediate include pharmaceutical R&D, fine chemical manufacturing, and academic research laboratories focused on heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage its unique sulfur-containing indane scaffold.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex organic molecules for material science and specialty chemical applications.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry, including studies on cyclization reactions and sulfur chemistry.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of novel aroma chemicals due to the structural features of the indane core.

Basic Information

Product Name	2-Hydroxy-1-Methylthioindane
CAS No.	101020-62-6
Molecular Formula	C10H12OS
Molecular Weight	180.27 g/mol
Synonyms	1-(Methylthio)-2-indanol; 2-Indanol, 1-(methylthio)-; 2-Hydroxy-1-(methylthio)indane; 1-Methylthio-2-hydroxyindane; 2-Hydroxy-1-methylmercaptoindane; 2-Hydroxyindan-1-yl methyl sulfide; 1-(Methylsulfanyl)indan-2-ol
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-1-Methylthioindane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.