Description

trans-1,2-Diamino-Cyclobutane Dihydrochloride is a high-purity, crystalline organic salt of significant interest in advanced chemical synthesis. This compound serves as a versatile and valuable chiral building block for constructing complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, asymmetric catalysis, and materials science.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer drug candidates.
• Ligand Synthesis: Used to prepare chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Research: Serves as a fundamental building block in academic and industrial research for exploring new cyclobutane-based chemistry and ring-strained systems.
• Peptidomimetics: Incorporated into the backbone of peptide analogs to confer conformational rigidity and enhance metabolic stability.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for developing specialty polymers with unique thermal and mechanical properties.
• Agrochemical Development: Employed in the research and synthesis of new, more selective crop protection agents.

Basic Information

Item	Details
Product Name	trans-1,2-Diamino-Cyclobutane Dihydrochloride
CAS No.	100959-95-3
Molecular Formula	C4H10N2 · 2HCl
Molecular Weight	159.06 g/mol
Synonyms	(1R,2R)-1,2-Diaminocyclobutane Dihydrochloride; (1S,2S)-1,2-Diaminocyclobutane Dihydrochloride; trans-1,2-Diaminocyclobutane Dihydrochloride; trans-1,2-Cyclobutanediamine Dihydrochloride; (R,R)-1,2-Diaminocyclobutane Dihydrochloride; (S,S)-1,2-Diaminocyclobutane Dihydrochloride; DACB Dihydrochloride; 1,2-trans-Diaminocyclobutane Dihydrochloride
EINECS	Contact for details

Quality Control

Our trans-1,2-Diamino-Cyclobutane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.