Description

6-Bromo-4,8-Dichloroquinazoline is a high-purity halogenated quinazoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its versatile reactivity, serving as a key building block for constructing complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinazoline-based drug candidates, including potential kinase inhibitors and anticancer agents.
• Agrochemical Research: Used to develop new herbicides, fungicides, and pesticides by acting as a core structural motif.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinazoline core into more complex molecules.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and colorants.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new reaction pathways involving halogenated heterocycles.

Basic Information

Product Name	6-Bromo-4,8-Dichloroquinazoline
CAS No.	100949-31-3
Molecular Formula	C8H3BrCl2N2
Molecular Weight	292.93 g/mol
Synonyms	4,8-Dichloro-6-bromoquinazoline; 6-Bromo-4,8-dichloroquinazoline; Quinazoline, 6-bromo-4,8-dichloro-; 100949-31-3; 6-Br-4,8-diCl-quinazoline; 4,8-Dichloro-6-bromo-quinazoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-4,8-Dichloroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.