Description

H-Pro-4M-Betana Hcl is a high-purity, non-natural amino acid derivative, specifically a proline analog, widely utilized in advanced pharmaceutical research and peptide synthesis. This compound is valued for its role in modifying peptide backbone structure and conformation, which is critical for developing novel therapeutic agents with enhanced stability and biological activity. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require specialized amino acid derivatives for drug discovery and development programs.

Application

• Pharmaceutical Intermediates: A critical building block in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce conformational constraints and improve metabolic stability.
• Proteomics & Biochemical Research: Employed as a tool compound in studying enzyme-substrate interactions, protein folding, and structure-activity relationships (SAR).
• Drug Discovery: Facilitates the development of peptide mimetics and constrained peptides for targeting challenging biological pathways.
• Bioconjugation: Can be used to create modified peptides for diagnostic applications and targeted drug delivery systems.

Basic Information

Product Name	H-Pro-4M-Betana Hcl
CAS No.	100930-07-2
Molecular Formula	C10H18N2O3 • HCl
Molecular Weight	250.72 g/mol (for HCl salt)
Synonyms	4-Methylproline Hydrochloride; (2S,4S)-4-Methylproline Hydrochloride; H-Pro(4-Me)-OH • HCl; L-4-Methylproline Hydrochloride; 4-Methyl-L-proline Hydrochloride; 4-Methylpyrrolidine-2-carboxylic acid hydrochloride; Proline, 4-methyl-, hydrochloride, (2S,4S)-; Betana, 4-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our H-Pro-4M-Betana Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific customer requirements, including research-grade and GMP-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.