Description

3-(4-(Trifluoromethyl)Phenoxy)Propan-1-Amine Hydrochloride is a high-purity organic intermediate featuring a trifluoromethylphenoxy moiety. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research institutions and industrial manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. The hydrochloride salt form offers enhanced stability and handling properties for synthetic applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science research.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex organic molecules, exploring new reaction pathways, and method development.
• Fine Chemical Production: Integral to the manufacture of specialty and performance chemicals requiring specific fluorinated aromatic structures.

Basic Information

Product Name	3-(4-(Trifluoromethyl)Phenoxy)Propan-1-Amine Hydrochloride
CAS No.	100840-63-9
Molecular Formula	C10H11F3NO • HCl
Molecular Weight	253.66 g/mol (Free base: 218.19 g/mol)
Synonyms	1-Propanamine, 3-[4-(trifluoromethyl)phenoxy]-, hydrochloride; 3-[4-(Trifluoromethyl)phenoxy]propylamine hydrochloride; 4-(Trifluoromethyl)phenoxypropylamine hydrochloride; 3-(4-Trifluoromethylphenoxy)propylamine HCl; γ-(4-Trifluoromethylphenoxy)propylamine hydrochloride; 1-Amino-3-(4-trifluoromethylphenoxy)propane hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(4-(Trifluoromethyl)Phenoxy)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.