Description

7-Nitro-2,3-dihydro-1H-indole is a versatile nitro-substituted indoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique fused-ring structure with a nitro group at the 7-position makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of bioactive molecules, particularly those targeting central nervous system (CNS) disorders, due to the indoline scaffold's prevalence in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the nitro group can be reduced or further functionalized to create active ingredients.
• Dye and Pigment Synthesis: Serves as a starting material for the production of specialized dyes and organic pigments, leveraging the aromatic system for color development.
• Material Science: Employed in the creation of advanced organic electronic materials, such as charge-transport layers or non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags or molecular probes for studying biological processes.
• Catalyst Ligand Synthesis: The nitrogen-containing heterocycle can be modified to create novel ligands for transition metal catalysis.

Basic Information

Product Name	7-Nitro-2,3-dihydro-1H-indole
CAS No.	100820-43-7
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	7-Nitroindoline; 2,3-Dihydro-7-nitro-1H-indole; 1H-Indole, 2,3-dihydro-7-nitro-; 7-Nitro-2,3-dihydroindole; 7-Nitroindoline (principal synonym); 7-Nitro-1H-indoline
EINECS	Contact for details

Quality Control

Our 7-Nitro-2,3-dihydro-1H-indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades, including research and pharmaceutical intermediate standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources, strong oxidizing agents, and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.