Description

m-Peg3-(Ch2)3-Alcohol CAS NO 100688-48-0 is a specialized polyethylene glycol (PEG) derivative featuring a terminal alcohol group, designed as a versatile linker and spacer molecule. This compound is critical for modifying the physicochemical properties of target molecules, enhancing solubility, and reducing immunogenicity in advanced formulations. It is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and material science industries for developing prodrugs, antibody-drug conjugates (ADCs), and functionalized polymers.

Application

• Pharmaceutical Linker: A key building block for constructing cleavable or non-cleavable linkers in Antibody-Drug Conjugates (ADCs) and targeted therapeutics.
• Prodrug Synthesis: Used to attach therapeutic agents via biodegradable bonds, improving drug solubility and enabling controlled release.
• Bioconjugation: Serves as a hydrophilic spacer to conjugate peptides, proteins, or dyes, minimizing steric hindrance and aggregation.
• Polymer Chemistry: Acts as a functional initiator or monomer for creating PEG-based hydrogels, coatings, and smart materials with tailored properties.
• Surface Modification: Employed to functionalize nanoparticles, biosensors, and diagnostic devices to improve biocompatibility and performance.
• Chemical Biology Tool: Utilized in probe and reagent development for studying biological processes and protein interactions.

Basic Information

Product Name	m-Peg3-(Ch2)3-Alcohol
CAS No.	100688-48-0
Molecular Formula	C11H24O5
Molecular Weight	236.31 g/mol
Synonyms	3,6,9-Trioxaundecane-1,11-diol, mono-methyl ether; 11-Hydroxy-3,6,9-trioxaundecan-1-ol; Methyl-PEG3-alcohol; mPEG3-(CH2)3-OH; 2-[2-[2-(3-Hydroxypropoxy)ethoxy]ethoxy]ethanol; PEG3 alcohol monomethyl ether; 3,6,9-Trioxa-1-undecanol, 11-methoxy-
EINECS	Contact for details

Quality Control

Our m-Peg3-(Ch2)3-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 15-25°C. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.