Description

(R)-2-Methyl-1-(m-Tolyl)Propan-1-Amine Hydrochloride is a high-purity chiral amine salt, a critical building block in advanced organic synthesis. Its enantiomeric purity makes it an indispensable intermediate for the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for creating novel compounds with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis, such as hydrogenation and cross-coupling reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require a defined stereochemical configuration.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in process chemistry.

Basic Information

Product Name	(R)-2-Methyl-1-(m-Tolyl)Propan-1-Amine Hydrochloride
CAS No.	100485-65-2
Molecular Formula	C11H17N·HCl
Molecular Weight	199.72 g/mol
Synonyms	(R)-1-(3-Methylphenyl)-2-methylpropylamine hydrochloride; (R)-α,2-Dimethyl-3-(methylamino)benzyl alcohol hydrochloride (tautomer); (R)-2-Methyl-1-(3-methylphenyl)propan-1-amine hydrochloride; (R)-m-Tolylisobutylamine hydrochloride; (R)-1-(m-Tolyl)-2-methylpropylamine HCl; (R)-3-Methylamphetamine hydrochloride (specific isomer); (R)-1-Amino-2-methyl-1-(3-methylphenyl)propane hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Methyl-1-(m-Tolyl)Propan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.