Description

1,4-Anhydro-D-Glucitol CAS NO 100402-56-0 is a high-purity, versatile sugar alcohol derivative and a key intermediate in fine chemical synthesis. This compound is valued for its role as a chiral building block and its utility in modifying the physical properties of formulations. It is essential for manufacturers and R&D teams in the pharmaceutical, cosmetic, and specialty chemical industries seeking reliable, high-quality intermediates for advanced applications.

Application

• Pharmaceutical intermediate for the synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Chiral building block in asymmetric synthesis for creating stereochemically complex molecules.
• Excipient and formulation aid in drug delivery systems to modify solubility and stability.
• Intermediate for producing surfactants and emulsifiers used in personal care and cosmetic products.
• Starting material for the synthesis of specialty polymers and biodegradable materials.
• Research and development reagent in carbohydrate chemistry and metabolic pathway studies.
• Additive in specialty chemical formulations requiring hygroscopicity control.

Basic Information

Product Name	1,4-Anhydro-D-Glucitol
CAS No.	100402-56-0
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	1,4-Anhydro-D-glucitol; 1,4-Anhydrosorbitol; D-Glucitol, 1,4-anhydro-; Isosorbide (Note: Isosorbide typically refers to 1,4:3,6-dianhydro-D-glucitol, a related compound); 1,4-Sorbitan; Anhydro-D-glucitol; 1,4-Anhydro-D-sorbitol
EINECS	Contact for details

Quality Control

Our 1,4-Anhydro-D-Glucitol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, chiral purity, and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.