Description

8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline is a specialized brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role as a versatile electrophilic building block, enabling the introduction of functionalized quinoline scaffolds into more complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in developing new crop protection agents and herbicides, leveraging the bioactivity of the quinoline core.
• Chemical Biology Probe Development: Serves as a starting material for creating fluorescent probes or affinity labels to study biological systems.
• Material Science Research: Potential building block for organic electronic materials or metal-organic frameworks (MOFs) due to its coordinating and conjugated structure.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline
CAS No.	100331-89-3
Molecular Formula	C18H14BrNO3
Molecular Weight	372.21 g/mol
Synonyms	5-(2-Bromoacetyl)-8-(phenylmethoxy)-2-quinolinol; 2-Hydroxy-8-benzyloxy-5-(2-bromoacetyl)quinoline; 8-Benzyloxy-5-bromoacetyl-2-hydroxyquinoline; 2-Quinolinol, 5-(2-bromoacetyl)-8-(phenylmethoxy)-; 5-(Bromoacetyl)-8-benzyloxy-2-hydroxyquinoline; 8-(Benzyloxy)-5-(2-bromoacetyl)quinolin-2-ol
EINECS	Contact for details

Quality Control

Our 8-Benzyloxy-5-(2-Bromoacetyl)-2-Hydroxyquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.