Description

[3Ar,(+)]-1,2,3,3Aα,4,5,8,8Aα-Octahydro-4α-Hydroxy-5β-Hydroxymethyl-2,2,8α-Trimethyl-6-Azulenecarbaldehyde CAS NO 100288-35-5 is a complex, high-purity sesquiterpenoid derivative with a defined stereochemistry. This compound is valued as a critical advanced intermediate or reference standard in sophisticated organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical and fine chemical sectors for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex terpenoid or azulene-based structures.
• Fine Chemical Synthesis: Used in the research and development of specialty chemicals, including fragrances, flavors, and advanced materials where its unique polycyclic framework is essential.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and impurity profiling in related chemical processes.
• Academic & Industrial Research: A valuable compound for studying stereoselective reactions, natural product synthesis, and the chemical properties of functionalized azulene derivatives.
• Process Chemistry Development: Used to optimize scalable synthetic routes for complex molecules, aiding in the development of cost-effective and efficient manufacturing processes.

Basic Information

Product Name	[3Ar,(+)]-1,2,3,3Aα,4,5,8,8Aα-Octahydro-4α-Hydroxy-5β-Hydroxymethyl-2,2,8α-Trimethyl-6-Azulenecarbaldehyde
CAS No.	100288-35-5
Molecular Formula	C₁₆H₂₆O₃
Molecular Weight	266.38 g/mol
Synonyms	(+)-4α-Hydroxy-5β-(hydroxymethyl)-2,2,8α-trimethyl-1,2,3,3aα,4,5,8,8aα-octahydro-6-azulenecarboxaldehyde; (3aR,4S,5R,8aS)-4-Hydroxy-5-(hydroxymethyl)-2,2,8a-trimethyl-3,3a,4,5,6,7,8,8a-octahydro-1H-azulene-6-carbaldehyde; 4α-Hydroxy-5β-(hydroxymethyl)-2,2,8α-trimethyl-1,2,3,3aα,4,5,8,8aα-octahydro-6-azulenecarboxaldehyde; A sesquiterpene aldehyde derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent oxidation and moisture uptake. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.