Description

Bicyclo[4.2.0]Octa-2,4-Diene-7-Carboxylic Acid (9Ci) is a specialized bicyclic, unsaturated carboxylic acid building block of significant interest in advanced organic synthesis. Its unique strained ring system and conjugated diene structure make it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and material science research. This high-purity intermediate is essential for chemists developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where precise stereochemistry and reactivity are critical.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, especially for creating complex, polycyclic core structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific, rigid molecular frameworks.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or optical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to construct intricate natural product analogs and complex organic molecules.
• Ligand and Catalyst Development: Utilized for synthesizing novel chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: A critical reagent for methodological studies and exploring new chemical spaces in university and industrial research settings.

Basic Information

Product Name	Bicyclo[4.2.0]Octa-2,4-Diene-7-Carboxylic Acid (9Ci)
CAS No.	100162-10-5
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	Bicyclo[4.2.0]octa-2,4-diene-7-carboxylic acid; 7-Bicyclo[4.2.0]octa-2,4-dienecarboxylic acid; 2,4-Bicyclooctadiene-7-carboxylic acid; (1R,6S)-Bicyclo[4.2.0]octa-2,4-diene-7-carboxylic acid; (1S,6R)-Bicyclo[4.2.0]octa-2,4-diene-7-carboxylic acid; Bicyclo[4.2.0]octadienecarboxylic acid; 7-Carboxybicyclo[4.2.0]octa-2,4-diene
EINECS	Contact for details

Quality Control

Our Bicyclo[4.2.0]Octa-2,4-Diene-7-Carboxylic Acid (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable performance in your most critical synthetic steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate to minimize degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.