Description

n-Boc-3-Aminophenol (CAS NO 19962-06-2) is a key protected intermediate in organic synthesis, valued for its role in constructing complex molecules. Its primary function is to introduce a protected amine group onto a phenolic scaffold, enabling selective reactions in multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its phenolic and protected amine functionalities are key structural components.
• Peptide Mimetics & Linker Chemistry: Serves as a versatile spacer or linker in the design of peptide analogs and bioconjugates, leveraging the orthogonal reactivity of the Boc-protected amine and phenol groups.
• Polymer & Material Science: Acts as a monomer or functionalization agent for creating specialty polymers with tailored properties, such as photosensitive resins or advanced coatings.
• Organic Synthesis Reagent: Employed in academic and industrial R&D laboratories for constructing complex heterocycles and other fine chemicals through coupling and deprotection sequences.

Basic Information

Product Name	n-Boc-3-Aminophenol
CAS No.	19962-06-2
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]phenol; 3-(Boc-amino)phenol; tert-Butyl (3-hydroxyphenyl)carbamate; 3-Aminophenol, N-Boc protected; 3-Hydroxybenzenamine, N-Boc derivative; Boc-3-aminophenol; N-Boc-3-hydroxyaniline
EINECS	Contact for details

Quality Control

Our n-Boc-3-Aminophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.