Description

L-(+)-Calciummandelate is the calcium salt of L-(+)-mandelic acid, a chiral compound of significant interest in fine chemical synthesis. This high-purity material is valued for its role as a key chiral intermediate and resolving agent in the production of optically active pharmaceuticals and agrochemicals. It is essential for research and manufacturing processes in the pharmaceutical, biotechnology, and advanced chemical synthesis industries where stereochemical purity is critical.

Application

• Pharmaceutical Intermediate: Used in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs requiring specific L-configuration stereochemistry.
• Chiral Resolution Agent: Employed for the separation of racemic mixtures of acids, amines, and other compounds in process development and manufacturing.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research involving mandelic acid derivatives.
• Agrochemical Synthesis: Acts as a building block for the production of chiral herbicides, fungicides, and plant growth regulators.
• Food & Flavor Industry: Potential use in the synthesis of chiral flavor compounds and food additives, subject to appropriate grade and regulatory compliance.
• Cosmetic Ingredients: Can be utilized in the development of specialty cosmetic actives where the mandelate moiety is desired for its properties.

Basic Information

Product Name	L-(+)-Calciummandelate
CAS No.	19944-53-7
Molecular Formula	C16H14CaO6 • xH2O
Molecular Weight	Anhydrous: 342.36 g/mol
Synonyms	Calcium L-(+)-mandelate; Calcium (2R)-2-hydroxy-2-phenylacetate; L-Mandelic acid calcium salt; (R)-(-)-Mandelic acid calcium salt; Calcium (R)-(-)-mandelate; Calcium (R)-2-hydroxy-2-phenylacetate; L(+)-Calcium mandelate; Calcium α-Hydroxybenzeneacetate (L-form)
EINECS	243-406-8

Quality Control

Our L-(+)-Calciummandelate is manufactured under a strict quality management system. Each batch is tested to ensure high chemical and optical purity, meeting the rigorous standards required for chiral intermediates. We provide comprehensive Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles. Specifications can be aligned with pharmaceutical (USP/EP) or custom requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking or decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (anhydrous basis)
Enantiomeric Excess (HPLC)	≥99.0%
Loss on Drying	≤2.0%
Heavy Metals	≤20 ppm
Residue on Ignition	22.0% - 24.0% (as CaO)
Specific Rotation [α]20/D	+150° to +158° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.