Description

[1R-(1Alpha,2Alpha,3Alpha,5Alpha)]-2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol is a high-purity, stereochemically defined terpene alcohol, a key chiral intermediate in advanced organic synthesis. Its precise stereochemistry makes it invaluable for creating optically active compounds with high enantiomeric purity, a critical requirement in pharmaceutical and fine chemical manufacturing. This product is essential for R&D chemists and production specialists in the pharmaceutical, agrochemical, and fragrance industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of terpene-based therapeutics and complex natural product analogs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where specific stereochemistry can significantly influence biological activity and environmental safety.
• Fragrance & Flavor Chemistry: Serves as a precursor for high-value aroma chemicals and flavorants, contributing piney, woody, or herbal notes due to its structural relationship to pinene derivatives.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a test substrate in the development and optimization of new asymmetric catalytic reactions.
• Fine Chemical Production: A versatile intermediate for synthesizing specialty chemicals, including dyes, photoresists, and advanced polymeric materials.
• Reference Standard: Used as an analytical standard in quality control laboratories for gas chromatography (GC) or high-performance liquid chromatography (HPLC) method development and validation.

Basic Information

Product Name	[1R-(1Alpha,2Alpha,3Alpha,5Alpha)]-2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol
CAS No.	19889-95-3
Molecular Formula	C10H18O
Molecular Weight	154.25 g/mol
Synonyms	(1R,2R,3R,5R)-3-Pinanol; (+)-trans-Pinanol; (1R,2R,3R,5R)-2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol; trans-Pinan-3-ol; 3-Pinanol, (1R,2R,3R,5R)-; d-trans-Pinanol; (1R,2R,3R,5R)-Pinan-3-ol
EINECS	243-379-6

Quality Control

Our [1R-(1Alpha,2Alpha,3Alpha,5Alpha)]-2,6,6-Trimethylbicyclo[3.1.1]heptan-3-ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the stringent requirements for use as a synthetic intermediate. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral GC/HPLC)	≥ 98.0% ee
Specific Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.