Description

(S)-(-)-1,2-Diaminopropane Dihydrochloride is a high-purity, chiral diamine salt widely used as a critical building block and resolving agent in asymmetric synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules, enabling precise control over the three-dimensional architecture of final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for antibiotics, antivirals, and neurological drugs.
• Asymmetric Catalyst Ligand: Used to synthesize chiral ligands for transition metal catalysts, which are crucial for enantioselective hydrogenation, oxidation, and cross-coupling reactions.
• Chiral Resolving Agent: Employed for the separation of racemic mixtures of carboxylic acids and other compounds via diastereomeric salt formation.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Polymer Modification: Incorporated into polymer backbones to impart chirality or functionality for advanced materials, such as chiral stationary phases for chromatography.
• Bioconjugation & Peptidomimetics: Utilized in the design and synthesis of peptide analogs and bioconjugates for drug delivery and diagnostic applications.

Basic Information

Product Name	(S)-(-)-1,2-Diaminopropane Dihydrochloride
CAS No.	19777-66-3
Molecular Formula	C3H10N2 · 2HCl
Molecular Weight	159.05 g/mol
Synonyms	(S)-1,2-Propanediamine Dihydrochloride; (S)-(-)-1,2-Diaminopropane Dihydrochloride; (S)-Propane-1,2-diamine Dihydrochloride; L-1,2-Diaminopropane Dihydrochloride; (S)-1,2-Diaminopropane Hydrochloride; (2S)-1,2-Diaminopropane Dihydrochloride; (S)-1,2-Diammoniopropane Dichloride
EINECS	Contact for details

Quality Control

Our (S)-(-)-1,2-Diaminopropane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards, including chiral purity (enantiomeric excess) and chemical purity. Certificates of Analysis (COA) detailing specific results for assay, identity, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.