Description

n-[[(Diethoxyphosphinothioyl)Thio]Acetyl]-L-Valine Ethyl Ester is a specialized organophosphorus compound that serves as a key chiral building block in advanced chemical synthesis. This high-purity intermediate is critical for developing active pharmaceutical ingredients (APIs) and agrochemicals with specific stereochemical requirements. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel, biologically active molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in antiviral and enzyme inhibitor drug candidates.
• Agrochemical Synthesis: Used as a key precursor in the manufacture of advanced pesticides and insecticides, where its specific stereochemistry can influence biological activity.
• Chemical Research: Employed in academic and industrial R&D laboratories for studying organophosphorus chemistry and developing new synthetic methodologies.
• Peptide Mimetic Development: Serves as a valine-derived building block for creating peptide analogs and mimetics with modified backbone structures.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for asymmetric catalysis and metal complexation.

Basic Information

Product Name	n-[[(Diethoxyphosphinothioyl)Thio]Acetyl]-L-Valine Ethyl Ester
CAS No.	19700-58-4
Molecular Formula	C13H26NO5PS2
Molecular Weight	371.45 g/mol
Synonyms	L-Valine, N-[[(diethoxyphosphinothioyl)thio]acetyl]-, ethyl ester; Ethyl N-[[(diethoxyphosphinothioyl)thio]acetyl]-L-valinate; O,O-Diethyl S-[(ethoxycarbonyl)-L-valyl]methyl phosphorodithioate; Acetyl-L-valine ethyl ester phosphorodithioate derivative; (S)-Ethyl 2-((((diethoxyphosphinothioyl)thio)acetyl)amino)-3-methylbutanoate; Valine phosphorodithioate ester; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of n-[[(Diethoxyphosphinothioyl)Thio]Acetyl]-L-Valine Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. All materials are characterized by modern analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.