Description

(R)-2,2'-Dimethyl-1,1'-Binaphthyl is a high-value, enantiomerically pure chiral compound belonging to the class of binaphthyl derivatives. This compound is a crucial chiral auxiliary and ligand in asymmetric synthesis, enabling the production of single-enantiomer pharmaceuticals and fine chemicals with high stereoselectivity. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors where precise molecular chirality dictates product efficacy and safety.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand or precursor for ligands (e.g., BINOL derivatives) in metal-catalyzed reactions such as hydrogenation, C-C bond formation, and oxidation.
• Pharmaceutical Intermediate: A key building block in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting central nervous system disorders, cardiovascular diseases, and infections.
• Chiral Resolution Agent: Used to separate racemic mixtures of acids, amines, or alcohols via diastereomeric salt formation or as a chiral stationary phase component in chromatography.
• Material Science: Employed in the development of chiral polymers, liquid crystals, and molecular devices for optoelectronics and sensors.
• Agrochemical Synthesis: A chiral synthon for creating enantiopure herbicides, fungicides, and plant growth regulators with improved environmental profiles.
• Academic & Industrial R&D: A fundamental tool for method development in organic chemistry and process chemistry for scale-up of chiral molecules.

Basic Information

Product Name	(R)-2,2'-Dimethyl-1,1'-Binaphthyl
CAS No.	19634-89-0
Molecular Formula	C22H18
Molecular Weight	282.38 g/mol
Synonyms	(R)-2,2'-Dimethylbinaphthyl; (R)-2,2'-Dimethyl-1,1'-binaphthalene; (R)-DM-BINAP (precursor); (R)-1,1'-Binaphthalene-2,2'-diyl-dimethyl; (R)-2,2'-Dimethyl-[1,1'-binaphthalene]; (R)-2,2'-Dimethyl-1,1'-binaphthyl; (R)-2,2'-Dimethyl-1,1'-binaphthalenyl; (R)-2,2'-Dimethyl-1,1'-dinaphthyl
EINECS	Contact for details

Quality Control

Our (R)-2,2'-Dimethyl-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for chiral intermediates. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (ee), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.