Description

1,3-Bis[(S)-2-Piperidinyl]-2-Propanone is a chiral organic compound featuring two (S)-configured piperidine moieties linked by a propanone bridge. This specific stereochemistry makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and fine chemical industries. The compound's structure is integral to the development of novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of potential drug candidates, particularly those targeting neurological and receptor-based pathways.
• Asymmetric Catalysis Ligand Precursor: Used in the development and preparation of chiral ligands for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex nitrogen-containing heterocycles and alkaloid analogs in academic and industrial research.
• Biochemical Research: Employed as a tool compound or reference standard in studies involving enzyme inhibition or receptor binding assays due to its defined stereochemistry.
• Agrochemical Development: Potential intermediate in the synthesis of novel, chiral active ingredients for crop protection agents.

Basic Information

Product Name	1,3-Bis[(S)-2-Piperidinyl]-2-Propanone
CAS No.	19519-53-0
Molecular Formula	C13H24N2O
Molecular Weight	224.34 g/mol
Synonyms	(S,S)-1,3-Di(2-piperidyl)-2-propanone; (S,S)-1,3-Dipiperidin-2-yl-propan-2-one; (2S,2'S)-1,1'-(2-Oxopropane-1,3-diyl)dipiperidine; (S)-1,3-Di(2-piperidyl)acetone; 1,3-Bis(2-piperidyl)-2-propanone, (S,S)-; 2-Propanone, 1,3-bis[(2S)-2-piperidinyl]-; (S,S)-Bis(2-piperidyl)acetone
EINECS	Contact for details

Quality Control

Our 1,3-Bis[(S)-2-Piperidinyl]-2-Propanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.