Description

1-Chloroisoquinoline is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactivity as an electrophile, enabling the construction of complex molecular architectures through cross-coupling and nucleophilic substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, serving as a key precursor for active pharmaceutical ingredients (APIs), functional ligands, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of bioactive molecules, including kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), conductive polymers, and other functional materials.
• Catalyst & Ligand Preparation: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Chemical Research: A valuable reagent for method development and exploring new reaction pathways in medicinal and synthetic chemistry.
• Dye & Pigment Industry: Acts as an intermediate in the production of complex dyes and organic pigments.

Basic Information

Item	Detail
Product Name	1-Chloroisoquinoline
CAS No.	19493-44-8
Molecular Formula	C9H6ClN
Molecular Weight	163.60 g/mol
Synonyms	Isoquinoline, 1-chloro-; 1-Chloro-isoquinoline; α-Chloroisoquinoline; NSC 403079; 1-Chloroisoquinoline; 1-Chloro-2-azanaphthalene
EINECS	Contact for details

Quality Control

Our 1-Chloroisoquinoline is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the rigorous demands of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.