Description

2,3-Dihydro-1-(Morpholinoacetyl)-3-Phenylquinazolin-4(1H)-One Monohydrochloride is a high-purity, synthetically derived pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key building block for the development of novel therapeutic agents, particularly in medicinal chemistry research. This compound is essential for B2B clients in the pharmaceutical, biotechnology, and fine chemical sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of more complex heterocyclic compounds due to its quinazolinone core and functionalized morpholine moiety.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for chemical methodology development and biological screening.

Basic Information

Product Name	2,3-Dihydro-1-(Morpholinoacetyl)-3-Phenylquinazolin-4(1H)-One Monohydrochloride
CAS No.	19395-78-9
Molecular Formula	C20H20N3O3·HCl
Molecular Weight	395.85 g/mol
Synonyms	1-(Morpholin-4-ylacetyl)-3-phenyl-1,2,3,4-tetrahydroquinazolin-4-one hydrochloride; 3-Phenyl-1-(2-morpholino-2-oxoethyl)-1,2,3,4-tetrahydro-4-quinazolinone hydrochloride; 1,2,3,4-Tetrahydro-3-phenyl-1-(2-morpholino-2-oxoethyl)-4-quinazolinone hydrochloride; 4(1H)-Quinazolinone, 2,3-dihydro-1-(morpholinoacetyl)-3-phenyl-, monohydrochloride; 19395-78-9; Morpholinoacetyl phenylquinazolinone hydrochloride
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-(Morpholinoacetyl)-3-Phenylquinazolin-4(1H)-One Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.