Description

Taurolidine is a synthetic antimicrobial and anti-endotoxin agent derived from the naturally occurring amino acid taurine. This compound is highly valued for its broad-spectrum biocidal activity and its unique ability to neutralize bacterial endotoxins, making it a critical component in infection control. It is essential for manufacturers in the pharmaceutical, medical device, and advanced wound care sectors seeking effective, non-antibiotic antimicrobial solutions. Taurolidine CAS NO 19388-87-5 represents a key building block for formulations requiring high-purity, reliable anti-infective properties.

Application

• Medical Device Coatings: Used to impregnate or coat central venous catheters, urinary catheters, and surgical meshes to prevent biofilm formation and device-related infections.
• Pharmaceutical Formulations: Serves as the active pharmaceutical ingredient (API) in antiseptic solutions for peritoneal dialysis, wound irrigation, and oral care products.
• Advanced Wound Care: Incorporated into hydrogels, gels, and dressings for managing chronic wounds like diabetic foot ulcers, leveraging its anti-biofilm and anti-inflammatory effects.
• Veterinary Medicine: Applied in topical antiseptic preparations and intrauterine infusions for the treatment of infections in livestock.
• Preservative Systems: Acts as a stabilizing and antimicrobial agent in diagnostic reagent kits and certain cosmetic formulations.
• Research & Development: Utilized in microbiological and immunological studies as a tool compound to investigate endotoxin neutralization and novel anti-infective strategies.

Basic Information

Product Name	Taurolidine
CAS No.	19388-87-5
Molecular Formula	C7H16N4O4S2
Molecular Weight	284.35 g/mol
Synonyms	Bis(1,1-dioxoperhydro-1,2,4-thiadiazinyl-4)methane; Tauroline; Taurolin; 4,4'-Methylenebis(tetrahydro-1,2,4-thiadiazine 1,1-dioxide); Tauroflex; Geistlich Taurolin; Taurolidine Dioxide; N,N'-(Methylenedi-4,1-phenylene)bis[1,1-dioxo-1,2,4-thiadiazinane]
EINECS	243-025-0

Quality Control

Our Taurolidine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting purity, related substances, residual solvents, and microbiological quality are provided with every shipment to support your regulatory and formulation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.