Description

6-Chloro-3,4-Dihydro-1H-Quinolin-2-One is a versatile and high-purity organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a key building block for constructing complex heterocyclic frameworks, enabling the development of novel compounds with targeted properties. This product is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its quinolinone core structure.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in advanced display and lighting technologies.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal-catalyzed reactions and organocatalysts.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized colorants and functional dyes.
• Academic and Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in research institutions and CROs.

Basic Information

Product Name	6-Chloro-3,4-Dihydro-1H-Quinolin-2-One
CAS No.	19358-40-8
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydro-2-quinolinone; 6-Chloro-2-oxo-1,2,3,4-tetrahydroquinoline; 6-Chloro-3,4-dihydro-2(1H)-quinolinone; 6-Chloro-1,2,3,4-tetrahydroquinolin-2-one; 2-Quinolinone, 6-chloro-1,2,3,4-tetrahydro-; 6-Chloro-2-tetrahydroquinolone
EINECS	Contact for details

Quality Control

Our 6-Chloro-3,4-Dihydro-1H-Quinolin-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.