Description

(3S)-3Aβ,4,5,8Bβ-Tetrahydro-3,4α,8-Trimethyl-4-Vinylbenzo[1,2-B:3,4-B']Difuran-2(3H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex, stereochemically defined benzodifuranone structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting complex biological pathways. It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the development of new active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of potential drug candidates, especially in oncology and CNS research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of benzodifuranone-based compounds.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale, requiring consistent high purity and stereochemical integrity.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes investigating novel heterocyclic compounds and their properties.
• Fine Chemical Synthesis: Used in the production of specialized, high-value chemicals for advanced material science and agrochemical research.
• Reference Standard: Can be supplied as a certified reference material for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	(3S)-3Aβ,4,5,8Bβ-Tetrahydro-3,4α,8-Trimethyl-4-Vinylbenzo[1,2-B:3,4-B']Difuran-2(3H)-One
CAS No.	19332-12-8
Molecular Formula	C17H20O3
Molecular Weight	272.34 g/mol
Synonyms	3,4α,8-Trimethyl-4-vinyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one; (3S)-3,4α,8-Trimethyl-4-vinyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one; Benzo[1,2-b:3,4-b']difuran-2(3H)-one, 3aβ,4,5,8bβ-tetrahydro-3,4α,8-trimethyl-4-vinyl-, (3S)-; 19332-12-8; 4-Vinyl-3,4α,8-trimethyl-3aβ,4,5,8bβ-tetrahydrobenzo[1,2-b:3,4-b']difuran-2(3H)-one; (3S)-Tetrahydro-3,4α,8-trimethyl-4-vinylbenzo[1,2-b:3,4-b']difuran-2(3H)-one
EINECS	Contact for details

Quality Control

Our (3S)-3Aβ,4,5,8Bβ-Tetrahydro-3,4α,8-Trimethyl-4-Vinylbenzo[1,2-B:3,4-B']Difuran-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ISO guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.