Description

3-(2,4-Dioxo-1,3-Diazaspiro[4.5]Dec-3-Yl)Propanoic Acid is a high-purity, specialized heterocyclic building block featuring a spirocyclic hydantoin core. This compound is valued for its unique molecular architecture, which serves as a critical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small molecule drugs, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the synthesis of advanced herbicides and fungicides, leveraging its spirocyclic structure for enhanced bioactivity.
• Peptidomimetics & Protease Inhibitors: The hydantoin moiety serves as a constrained scaffold in designing peptide mimics and enzyme inhibitors.
• Material Science: Acts as a precursor for functional polymers and advanced organic electronic materials due to its rigid, conjugated backbone.
• Chemical Biology Probes: Utilized in medicinal chemistry for creating tool compounds and probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in multi-step synthetic routes for client-specific molecules.

Basic Information

Product Name	3-(2,4-Dioxo-1,3-Diazaspiro[4.5]Dec-3-Yl)Propanoic Acid
CAS No.	19282-94-1
Molecular Formula	C₁₂H₁₈N₂O₄
Molecular Weight	254.28 g/mol
Synonyms	3-(2,4-Dioxo-1,3-diazaspiro[4.5]dec-3-yl)propanoic acid; 3-(2,4-Dioxo-1,3-diazaspiro[4.5]decan-3-yl)propanoic Acid; 3-(2,4-Dioxo-8-azaspiro[4.5]dec-3-yl)propanoic Acid; 3-(2,4-Dioxo-1,3-diazaspiro[4,5]decane-3-yl)propanoic Acid; 1,3-Diazaspiro[4.5]decane-2,4-dione, 3-(2-carboxyethyl)-; Propanoic acid, 3-(2,4-dioxo-1,3-diazaspiro[4.5]dec-3-yl)-; Spirohydantoin propanoic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 3-(2,4-Dioxo-1,3-Diazaspiro[4.5]Dec-3-Yl)Propanoic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets a typical purity of ≥97% (HPLC), with higher purity grades available. A detailed Certificate of Analysis (COA) providing full specifications, including chromatographic data and impurity profiles, is supplied with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.